Makoto Yamashita Selected Research

2- (4- (2- (diethylamino)ethoxy)phenyl)- N- (2,4- difluorobenzyl)- 5- fluoropyrimidin- 4- amine

1/2010

RS-1748, a novel CC chemokine receptor 4 antagonist, inhibits ovalbumin-induced airway inflammation in guinea pigs.

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Makoto Yamashita Research Topics

Disease

22	Human Influenza (Influenza) 01/2020 - 08/2002
15	Infections 01/2020 - 02/2003
5	Chronic Obstructive Pulmonary Disease (COPD) 01/2019 - 10/2008
5	Thymoma (Thymic Carcinoma) 01/2017 - 08/2013
4	Body Weight (Weight, Body) 01/2020 - 01/2011
4	Inflammation (Inflammations) 08/2019 - 08/2005
3	Virus Diseases (Viral Diseases) 01/2019 - 02/2010
3	Fibrosis (Cirrhosis) 08/2017 - 01/2016
3	Respiratory Tract Infections (Respiratory Tract Infection) 09/2012 - 05/2012
3	Asthma (Bronchial Asthma) 01/2010 - 09/2004
3	Respiratory Hypersensitivity 10/2008 - 08/2004
2	Anorexia Nervosa 01/2020 - 01/2020
2	Atopic Dermatitis (Atopic Eczema) 10/2010 - 12/2009
2	Influenza in Birds (Avian Flu) 02/2010 - 01/2010
2	Cough 10/2008 - 05/2008
2	Allergic Rhinitis 10/2008 - 03/2005
2	Respiratory Tract Diseases (Respiratory Tract Disease) 10/2008 - 05/2008
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Rheumatoid Arthritis 01/2019
1	Hypertension (High Blood Pressure) 11/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018
1	Adenocarcinoma 01/2018
1	Adenocarcinoma of Lung 01/2018
1	Edema (Dropsy) 01/2018
1	Ebola Hemorrhagic Fever 12/2017
1	Sepsis (Septicemia) 12/2017
1	Idiopathic Pulmonary Fibrosis 01/2017

Drug/Important Bio-Agent (IBA)

13	Neuraminidase (Sialidase)IBA 08/2019 - 08/2002
9	Zanamivir (Relenza)FDA Link 08/2010 - 08/2002
8	laninamivirIBA 08/2019 - 01/2009
6	CS 8958IBA 10/2013 - 01/2009
5	OvalbuminIBA 10/2010 - 08/2004
5	Oseltamivir (Tamiflu)FDA Link 08/2010 - 01/2009
4	Pharmaceutical PreparationsIBA 01/2020 - 01/2010
3	VaccinesIBA 09/2019 - 01/2019
3	Bleomycin (Blenoxane)FDA LinkGeneric 08/2017 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 12/2014 - 01/2011
3	ProdrugsIBA 03/2010 - 06/2009
3	Methacholine Chloride (Methacholine)FDA Link 10/2008 - 08/2004
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2020
2	LipidsIBA 01/2020 - 01/2017
2	Hemagglutinins (Hemagglutinin)IBA 09/2019 - 02/2003
2	Influenza Vaccines (Influenza Vaccine)FDA Link 09/2019 - 01/2019
2	pirfenidoneIBA 01/2019 - 01/2017
2	SmokeIBA 01/2019 - 01/2019
2	LipopolysaccharidesIBA 01/2019 - 10/2010
2	pyrimidineIBA 09/2012 - 05/2012
2	AntigensIBA 07/2012 - 08/2005
2	Immunoglobulin E (IgE)IBA 07/2012 - 08/2005
2	Surface-Active Agents (Surfactants)IBA 01/2012 - 01/2011
2	CCR4 ReceptorsIBA 10/2010 - 01/2010
2	Phosphates (Orthophosphate)IBA 03/2010 - 01/2009
2	Capsaicin (Zostrix)FDA Link 10/2008 - 08/2004
2	1- (2- (2- (3,4- dichlorophenyl)- 4- (3,4,5- trimethoxybenzoyl)morpholin- 2- yl)ethyl)spiro(benzo(c)thiophene- 1(3H),4'- piperidine)- 2- oxideIBA 10/2008 - 05/2008
1	baloxavirIBA 01/2020
1	Viral HemagglutininsIBA 01/2020
1	Staphylococcal Protein A (Protein A)IBA 01/2020
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2020
1	Nucleic Acid Synthesis InhibitorsIBA 08/2019
1	CalciumIBA 01/2019
1	GalactosidasesIBA 01/2019
1	AntibodiesIBA 01/2019
1	InterleukinsIBA 01/2019
1	IronIBA 01/2019
1	LigandsIBA 01/2019
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2019
1	8-Hydroxy-2'-DeoxyguanosineIBA 01/2019
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	TensinsIBA 01/2019
1	PTEN-induced putative kinaseIBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2019
1	ChemokinesIBA 01/2019
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2019
1	Sirolimus (Rapamycin)FDA Link 01/2019
1	aluminum sulfate (alum)IBA 01/2019
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2019
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 01/2019
1	SodiumIBA 11/2018
1	GoldIBA 02/2018
1	25-hydroxyvitamin DIBA 01/2018
1	Vitamin D FDA LinkGeneric 01/2018
1	Ion Channels (Ion Channel)IBA 01/2018
1	Clonidine (ST 155)FDA LinkGeneric 01/2018
1	hydroxide ionIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 12/2017
1	EnzymesIBA 12/2017
1	Azithromycin (Zithromax)FDA LinkGeneric 08/2017
1	Proteasome Endopeptidase Complex (Proteasome)IBA 08/2017
1	NADPH Oxidase 4IBA 08/2017

Therapy/Procedure

5	Thymectomy 01/2017 - 08/2013
4	Therapeutics 08/2019 - 01/2012
4	Oral Administration 08/2019 - 03/2005
3	Intranasal Administration 10/2010 - 06/2009
1	Aftercare (After-Treatment) 01/2020
1	Pneumonectomy (Lung Volume Reduction) 01/2019
1	Minimally Invasive Surgical Procedures 01/2017